What can we learn from traumatized rats about Post-traumatic Stress Disorder?
Tarih:
Konum: A216
Post-traumatic Stress Disorder (PTSD) is thought to reflect learned associations between neutral events and life threatening situations that persist well after the life threatening condition subsides. In technical terms, PTSD patients are thought to exhibit extinction deficits in their previously conditioned fear. To gauge the potential neurobiological mechanisms of PTSD, extinction of classically conditioned fear responses in rodents along with their neural signatures have been widely investigated. In my talk, I am going to mention the involvement of specific inhibitory cell populations referred as the intercalated cells, in the amygdala in extinction of classically conditioned fear and how these neurons might be promising targets for future treatment strategies of PTSD patients.
Çağrı Temuçin Ünal, PhD